Bio-industry and chemical technology mutually leveraging upgrade

All of the world's top chemical companies are investing in biotechnology research, and the bio-industry will become the fastest growing economic sector. In China, biotechnology, represented by molecular biology, cell biology, fermentation engineering, and enzyme engineering, has played a major role in the fields of medicine, agriculture, energy, environmental protection, food, materials, textiles, and construction. The development of the bio-industry depends not only on breakthroughs in chemical technology, but also on promoting the upgrading of traditional chemical industries.

Industrial Biotechnology: Set off Green Manufacturing**

Industrial biotechnology industries such as bio-energy, bio-environmental protection, and bio-manufacturing will be the areas of rapid development in the bio-industry, and are also emerging industries that China should strengthen its technical development and follow up in a timely manner. Raising modern fermentation, biocatalysis and other technologies to create an industrial biotechnology industry are of great significance for promoting the upgrading of the traditional chemical industry and promoting the development of green manufacturing. It is an urgent requirement to ease fossil energy shortages, ensure national energy security, and implement a recycling economy. By 2020, the proportion of biomass energy in the world's energy consumption will reach about 5%, bio-based materials will replace 10% to 20% of chemical materials, and biological production of fine chemicals will replace 30% to 60% of chemical methods. .

To develop bio-industries, basic research and industrialization of major technologies need to be strengthened, and biotechnical standards such as enzyme engineering and fermentation engineering should be improved, and the transformation of traditional chemical manufacturing should be accelerated. Highlights include the development of biofuels, solvents, amino acids and organic acids, functional food additives, biomaterials, biochemical products, etc., and use of renewable biomass feedstocks to produce ethanol, lactic acid, 1,3-propanediol, and 1,4-butanediol. , succinic acid and other platform compounds, expanding the scale of production of bulk raw materials chemicals such as ethylene, polylactic acid, and cellulose and biomaterials, supporting biodegradable solvents, lubricants, green surfactants, epoxy curing agents, polyesters (ethers) ) Development of industrialization technologies for green fine chemicals such as polyols, focusing on the scale of biosynthesis of functional foods and health products such as lysine, glutamic acid, malic acid, xylitol, and citric acid. In the field of bio-environment protection, we should speed up the promotion and application of new technologies and new equipment for green production processes such as bio-bleaching, bio-pulping, bio-tanning, and bio-dilution, and focus on the development of high-performance water treatment flocculants, coagulants, and other biotechnologies. Products, encourage the research and industrialization of wastewater treatment, garbage disposal, and ecological restoration biotechnology products.

Agricultural biological products: Transforming the traditional agro-chemical industry Agriculture is the basis of national economy and people's livelihood, and also the stage for the development of biotechnology. Especially in the field of pesticides and fertilizers, the development of agricultural biological products such as biological pesticides and biological fertilizers has a major bearing on agricultural development.

The use of biotechnology to develop bio-pesticides has the advantages of wide source of resources, low pollution and low residue. The promotion of biological pesticides is an important way to achieve sustainable development of modern agriculture and forestry, protect the safety of the ecological environment, and develop green agriculture. At present, China's biological pesticides lack of supporting technologies in diagnostics, preparation processes, environmental monitoring and other links, and the industrial system is not perfect. We should focus on the use of biotechnology for pathological, pharmacological, metabolic research and development, formulate standards for biological pesticides, etc., and strengthen the innovation of biological pesticide companies. Capacity and industrial competitiveness, improve microbial pesticides, plant-derived pesticides, biochemical pesticides, genetically modified pesticides and natural enemies biological pesticide development technology, the development of new biological pesticides such as virus preparations, fungal preparations, protein preparations, oligochitosan preparations.

In the field of chemical fertilizers, the use of biotechnology can effectively improve the use of chemical fertilizer products, promote energy conservation and emission reduction, and achieve industrial upgrading and upgrading in light of the fact that conventional chemical fertilizers are fast-acting and low-utilization. The use of biological enzyme activators by adding phosphate fertilizer to produce biological enzymes to activate phosphate fertilizer can reduce the fixation of soil phosphorus and loss of nitrogen, increase the utilization rate of phosphorus and prolong the effect of fertilizer. The addition of metalloproteinase to urea can also effectively increase the production of polypeptide urea. Nitrogen fertilizer utilization.

Bio-medicines: scale up and reach the high-end As the bio-industry's key and high-end bio-pharmaceutical industry, China has exposed the problems of small industrial scale, weak capacity for independent innovation, and low conversion rate of results. At present, the main products of biochemical raw materials are antibiotics, vitamins, amino acids, organic acids, etc. Many products have low technological content, low added value, high energy consumption, and high pollution. Especially in the high-end fields such as biotechnology raw material medicines, due to the high investment in industrial R&D and the difficulty in transforming achievements, domestic products are mainly based on imitation. China's biopharmaceutical technology patents are obviously less, and the number of listed patented products is even less. Currently, biotechnology patents in the world account for 59%, 19%, and 17% of the US, Europe, and Japan respectively, and only 5% of developing countries including China.

China's bio-pharmaceutical industry must focus on the development of high-tech products based on modern cutting-edge technologies, change the existing mode of production of bio-pharmaceutical companies, further strengthen independent innovation capabilities, build a relatively complete industrial chain, and foster core competitiveness as soon as possible. Leading enterprises and a large number of well-developed SMEs; Formation of a large number of large-scale bio-enterprises with independent technology, focusing on breakthroughs in the restructuring of major products with ************* and granulocyte colony-stimulating factor Albumin, as well as biotechnology APIs such as monoclonal antibodies and vaccines.

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